The American Indians highly valued goldenseal. It has anti-microbial properties and fights off disease-causing organisms. It prevents bacteria from attaching to cells, boosts the immune system, reduces fevers, and prevents cancer. It can treat inflammatory digestive disorders, relieve menstrual pain, and treat respiratory infections. It has been used as a mouthwash and to heal skin infections. Goldenseal should not be used by pregnant women and those with high blood pressure.