VitaBoost10™ Premix for Gluten-Free Applications

For those who suffer from a digestive disorder, it can be especially important to eat a balanced diet, choosing foods that are a good source of vitamins and minerals. VitaBOOST10™ is a vitamin-mineral premix that contains ten essential vitamins and minerals that dieticians recommend those with celiac disease and other digestive disorders make a part of their regular diet.

Celiac disease is an autoimmune disorder that damages the villi in the small intestine, making it hard for those with the disease to absorb nutrients in food. For this reason, those with celiac disease are more susceptible to developing vitamin and mineral deficiencies. To compound this problem, many gluten-free products are not enriched and have lower amounts of the vitamins found in wheat-based products, such as iron, folate, thiamin, niacin, and riboflavin. A recent study by the UV University Medical Centre Department of Nutrition and Department of Gastroenterology in Amsterdam found that 87% of untreated celiac patients suffer from at least one nutritional deficiency and many others suffer from multiple deficiencies¹.

VitaBOOST10™ contains ten nutrients that dieticians recommend those with celiac disease make part of their regular diet to counteract the risk of developing deficiencies.

Nutritional Consideration	Nutrient Involved	RecommendedDaily Value (DV)*	Facts & Figures
Folate Deficiency/ Spina Bifida	Folate	400 mg	Folate deficiency may occur in severe cases of malabsorption Folate intake is especially important for women with celiac disease who are planning a pregnancy or are pregnant² In pregnant women a deficiency can cause neural tube defects in the baby, also known as spina bifida
Iron Deficiency/ Anemia	Iron	18 mg	Iron deficiency anemia is common with celiac disease² Up to 50% of celiac patients reported that they had been diagnosed with iron deficiency anemia and 45% of celiac patients reported having persistent low iron storage (low ferritin) two years post diagnosis³ Iron deficiency will persist until guy morphology is restored and iron stores are replenished
Osteopenia or Osteoporosis	CalciumVitamin D	1,000 mg400 IU	Early bone disease is common in both men and women with celiac disease, with studies suggesting up to 70% of celiac patients have reduced bone mineral density³ The high prevalence of osteoprorosis in celiac disease warrants a Bone Mineral Density (BMD) be ordered at time of diagnosis Vitamin D deficiency is common in celiac disease because it is absorbed in the region most damaged by celiac disease Calcium deficiencies arise as a result of vitamin D deficiencies with only 10-15% of dietary calcium being absorbed due to low vitamin D levels (compared to 30-40% in healthy individuals) Osteoporosis may persist even with strict adherence to the gluten-free diet Adult celiac patients on a gluten-free diet with adequate calcium intake for four years had reduced fractional calcium absorption and BMD compared with control subject despite the remission in their clinical symptoms
Thiamin Deficiency/ BeriBeri	Thiamin (B₁)	1.5 mg	Thiamine helps to process carbohydrates, fats and proteins and is needed for memory and other brain functions⁴ Since Thiamine is mostly found in whole-grain and enriched wheat grain products those with celiac disease struggle to add it to their diet Thiamine deficiency may occur in severe cases of malabsorption Severe deficiency can result in beriberi, which damages the heart and nervous system Thiamine deficiency can also lead to a decrease in mental status and vision, memory problems, confusion, emotional changes and heart failure.
Riboflavin Deficiency	Riboflavin (B₂)	1.7 mg	More than 34% of Americans get less than the recommended DV because, unlike many other vitamins, it is not found in many foods⁵ Riboflavin is essential for growth and production of red blood cells and maintaining healthy skin, eyes, hair and nervous system. Riboflavin deficiency is common before starting a gluten-free diet as it can be depleted through diarrhea, a common side effect of untreated celiac disease
Niacin Deficiency/ Pellargra	Niacin (B₃)	20 mg	Niacin deficiency is common in celiac disease Niacin deficiency slows metabolism and impairs functioning of the brain, nervous system and digestive tract⁵ Pellagra may occur in severe cases of malabsorption, which causes bloody diarrhea, dermatitis and dementia
Pyridoxine Deficiency	Vitamin B₆	2 mg	Pyridoxine deficiency is found in 14% of those with untreated celiac disease¹ Lack of pyridoxine can lead to anemia, high blood pressure, eye inflammation, depression, water retention, dermatitis, mouth lesions and hair loss
Vitamin B12 Deficiency	Vitamin B₁₂	6 mg	Although celiac disease predominately affects the proximal bowel, vitamin B12 deficiency is found in up to 40% of celiac patients³ B12 is important for red blood cell formation and healthy neurological function³ Deficiency can result in peripheral neuropathy and numbness in the extremities. Deficiency should normalize with strict adherence to a gluten-free diet
Zinc Defficiency	Zinc	15 mg	Most Americans are deficient in zinc, consuming less than 10 mg per day. This deficiency is exacerbated in those with celiac disease⁵ Zinc is essential for the activity of approximately 100 enzymes that promote biochemical reactions in the body Zinc is also essential in the support of a healthy immune system, wound healing and DNA synthesis
FDA. Guidance for Industry: A Food Labeling Guide (14. Appendix F: Calculate the Percent Daily Value for the Appropriate Nutrients).¹ Wierdsma, N; Bokhorst-de van der Schueren, M; Berkenpas, M; Mulder, C; van Bodegraven, A. Vitamin and Mineral Deficiencies Are Highly Prevalent In Newly Diagnosed Celiac Disease Patients. Nutrients* 2013.² Canadian Celiac Association. www.CeliacGuide.org³Watson, L. Nutrient Deficiencies in Celiac Disease. http://drlisawatson.com/nutrient-deficiencies-celiac⁴ Schulte, S. Thiamine (B₁). Beth Israel Deaconess Medical Center. http://www.bidmc.org/YourHealth/Conditions-AZ/Celiac-disease-Celiac-sprue.aspx?ChunkID=26273⁵ Libonati, Cleo. Recognizing Celiac Disease, Fort Washington, PA, USA: GFW. Publishing 2007. www.recognizingceliacdisease.com

Perfect for all gluten-free applications, VitaBOOST10™ is formulated to provide 15% of the daily value of these vitamins and minerals per serving. All of Watson’s nutritional premixes are formulated with assay-verified ingredients and undergo physical and chemical tests by validated analytical procedures prior to being released for shipment so you can be sure that your products meet label claim. Click here to learn more about Watson’s Quality Control Program.

All of Watson’s gluten-free products, including this premix, are certified gluten-free by the Gluten Intolerance Group. Click here to learn more about Watson’s Certification Programs.